Granulomatous Cheilitis: A Case Report

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Jordan Genece
Justin Chu
Stephanie Liu
Nahla Shihab
Jonathan Ungar


granulomatous cheilitis, intralesional triamcinolone, benzocaine gel


Introduction: Granulomatous cheilitis is a rare condition, with an unknown etiological pathway, resulting in inflammation of the lips. This case report demonstrates the efficacy of intralesional triamcinolone with this persistent disorder.

Case report: A 19-year old man presented with orofacial swelling on the right side for approximately 18 months. Previous treatments of minocycline and metronidazole were unsuccessful. The patient has no other symptoms and an unremarkable family history. A regiment of topical anesthetic and intralesional triamcinolone showed significant improvement.

Discussion: This rare condition has many possible contributory factors with very few established treatments. Our patient appeared to present either granulomatous cheilitis or monosymptomatic Melkersson-Rosenthal syndrome. Our primary goal was to abate the patient’s symptoms for their comfort, hence the implication of the benzocaine gel.

Conclusion: There are various therapeutic methods described, however, we believe intralesional triamcinolone injections with prior application of topical anesthetic to ease discomfort, could be an alternative treatment.



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