A Diagnostic Challenge: Desmoplastic Melanoma

Main Article Content

Katie O'Connell
Ryan Svoboda
Bryan Anderson
Klaus Helm
Kimberly Ken

Keywords

melanoma, desmoplastic melanoma, oncology, pigmented lesion

Abstract

Desmoplastic melanoma (DM) is uncommon and can be a diagnostic challenge both clinically and histologically. We report a unique presentation of DM presenting as an amelanotic, depressed, indurated plaque on the forehead. The lesion was clinically concerning for a morpheaform basal cell carcinoma and with an unrevealing initial punch biopsy, an excisional biopsy with IHC was necessary to determine a diagnosis of pure desmoplastic melanoma. When a patient presents with a depressed, indurated plaque of unknown etiology, including DM in the clinical differential diagnosis and communicating this to the dermatopathologist can potentially reduce the risk for a delay in diagnosis.

References

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