“They Won’t Let Me Return to Work.” A Carpenter Diagnosed with Porphyria Cutanea Tarda

Main Article Content

Max A Schaefer
Maulik M Dhandha
Jonathan B Karnes

Keywords

Porphyria cutanea tarda

Abstract

Porphyria cutanea tarda (PCT) is characterized by a skin blistering eruption that develops in sun exposed areas of the skin. It is the most common cutaneous porphyria world-wide, and classically associated with hepatic injury but also estrogen use, cigarette smoking, and HIV. In any case of photodistributed persistent blistering skin condition, PCT must be high on the differential. This case of a carpenter diagnosed with PCT not only illustrates a classic case but also the opportunity to achieve significant response to therapy in a motivated patient particularly with improved access to direct-acting antivirals (DAA) for hepatitis C treatment.

References

1. Puy H, Gouya L, Deybach JC. Porphyrias. Lancet. 2010; 375:924-937.

2. Jalil S, Grady JJ, Lee C, et al. Associations among behavior-related susceptibility factors in porphyria cutanea tarda. Clinical Gastroenterology Hepatology. 2010; 8:297-302. el.

3. Sarkany RP. The management of porphyria cutanea tarda. Clinical Expermental Dermatology. 2001; 26:225-232.

4. Hall, B.J. & Hall, J. C. Saunders Manual of Skin Diseases Hall, Eleventh edition. Philadelphia: Wolters Kluwer Health; 2017. pp

5. Bissell M, Anderson K.E., & Bonkovsky, M.D. Porphyria. New England Journal of Medicine. 2017; 377: 862-872.