A Rare Case of Angiolymphoid Hyperplasia without Eosinophils, with Review of the Literature

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James Ko
Zachary P Nahmias
Patrick S Phelan http://orcid.org/0000-0003-1637-5854
Sabra Abner
Kara Blackwell
Andras Schaffer


angiolymphoid hyperplasia with eosinophils, ALHE, epithelioid hemangioma, vascular proliferation


The epithelioid hemangioma, more commonly termed angiolymphoid hyperplasia with eosinophils, is a pathologic vascular proliferation characterized by a distinctive eosinophil-rich mixed inflammatory infiltrate. A nonspecific accompanying infiltrate has only rarely been reported, and may confound the diagnosis of this benign process with malignant mimics. We present such a case of angiolymphoid hyperplasia without eosinophils, and consider its diagnosis and pathogenesis within the spectrum of related entities.


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