Blistering Rash over Broken Ribs

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Kathleen R Graham
Bethany R Rohr
Victor J Marks


Fracture blisters, management of fracture blisters, blistering disorder, blisters, trauma


Fracture blisters are painless fluid-filled bullae most commonly located over fractures of the distal tibia and humerus. They are diagnosed clinically. Invasive procedures and treatments increase the risk of wound infection and should be avoided. While there is no consensus on management, evidence supports leaving the blisters intact and treating erosions with topical barrier ointments or topical antibiotics. We present a rare case of a 55-year-old man with fracture blisters located superficial to trauma-induced rib fractures that were successfully treated with topical mupirocin.


1. Varela C, Vaughan TK, Carr J, et al. Fracture Blisters: Clinical and Pathologic Aspects. J of Orthopedic Trauma. 1993;7(5):417–27.

2. Wallace GF, Sullivan J. Fracture Blisters. Clin Podiatric Med Surg. 1995;12(4):801–12.

3. Giordano CP, Koval KJ, Zuckerman JD, Desai P. Fracture blisters. Clin Orthop Relat Res. 1994;(307):214-221.

4. Strauss E, Petrucelli G, Bong M, Koval K, Egol K. Blisters Associated with Lower Extremity Fracture: Results of a Prospective Treatment Protocol. J of Orthopedic Trauma. 2006 Oct;20(9):618–622.

5. Ballo F, Maroon M, Millon SJ. Fracture blisters. J Am Acad Dermatol. 1994;30:1033-1034.

6. Finklea LB, Becker LE. Hemorrhagic and serous-filled vesicles and bullae. Fracture blisters. JAMA Dermatol. 2013;149:751-756.

7. Tan CP, Ng A, Civil I. Co-morbidities in trauma patients: common and significant. N Z Med J. 2004;117:U1044.

8. Uebbing CM, Walsh M, Miller JB, Abraham M, Arnold C. Fracture Blisters. West J Emerg Med. 2011;12(1):131-133.

9. Halawi MJ. Fracture Blisters After Primary Total Knee Arthroplasty. Am J Orthop. 2015;44(8):E291-E293.