Long Term Follow Up of Cutaneous Sinus Histiocytosis (Rosai-Dorfman Disease)
Rosai-Dorfman disease is a benign histiocytic proliferative disorder of unknown etiology with cutaneous variants clinically presenting with painless cervical lympadenopathy, fever, leukocytosis and other systemic findings.1 Although the skin is the most common extranodal site, rare purely cutaneous forms of the disease exist and diagnosing such case rests solely on histopathologic findings.2
We report a case with a fifteen year follow up period of this uncommon disorder and describe itsclinical course marked by multiple episodic recurrences.
Rosai J, Dorfman RF. Sinus histiocytosis with massive lymphadenopathy. A newly recognized benign clinicopathologic entity. Arch Pathol. 1969;87:63-70.
Stefanato CM, Ellerin PS, Bhawan J. Cutaneous sinus histiocytosis (Rosai-Dorfman disease) presenting clinically as vasculitis. J Am Acad Dermatol. 2002;46:775-778.
Goodman WT, Barrett TL. Histiocytoses. In: Bologna JL, Jorizzo JL, Rapinin RP, eds. Dermatology. Vol 2. London; New York: Mosby;2003:1429-1445.
Traboulsi D. Robertson L. Rosai-Dorfman disease presenting as chronic sinusitis and joint pain with associated facial plaques. J Am Acad Dermatol. 2017;76:AB 222.
Mirvish E, Geskin L, Pomerantz R. A case of cutaneous Rosai-Dorfman disease. J Am Acad Dermatol. 2013;68:AB 38.
Brenn T, Calonje E, Granter SR, Leonard N, Grayson W, Fletcher CD, McKee PH. Cutaneous Rosai-Dorfman disease is a distinct clinical entity. Am J Dermatopathol. 2002;24:385-391.
Miceli A, Cleaver N, Spizuoco A. Rosai-Dorfman disease. Cutis. 2015;96:16, 39-40.
Khan A, Musbahi E, Suchak R, Mehta RK, Khorshid SM, Ozua P. Cutaneous Rosai-Dorfman disease treated by surgical excision and a review of the literature. J Am Acad Dermatol. 2015;72:AB 259.
Chinthapali S, Cerio R, Harwood C. Cutaneous Rosai-Dorfman disease: A rare clinical entity. J Am Acad Dermatol. 2017;76:AB 91.
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