Review of Tumor Margins for Lentigo Maligna with Staged Surgical Excision and Permanent Section en face Processing
Main Article Content
Keywords
lentigo maligna, en face surgical margins, staged surgical excision, immunostaining, permanent paraffin section, MITF
Abstract
Background: The optimal surgical margins required for the excision of lentigo maligna remains a topic of debate. Recent literature suggests that wider margins are warranted.
Objective: Comparison of lentigo maligna margin sizes and clearance rates from a single center to existing literature.
Methods: A retrospective analysis of primary and recurrent lentigo maligna treated by staged excision with complete circumferential and deep margin assessment between 2011 and 2023 at a single institution was conducted. The percentage of tumors with clear margins after the initial excision with 5 mm margins was determined.
Results: A total of 65 tumors were identified. Fifty-eight patients (89.2%) had clear margins after initial excision with 5 mm margins.
Conclusions: This study reports a higher percentage of lentigo maligna clearance following the initial staged excision with 5 mm margins than reports in the literature. These differences may be attributed to variations in section processing, staining techniques, and factors associated with differences in subclinical spread.
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