Main Article Content
mycobacterium haemophilum, crusted scabies, iatrogenic, immunocompromised
Mycobacterium haemophilum and crusted scabies are rare cutaneous diseases reported in distinct immunocompromised hosts. M. haemophilum is a skin and soft tissue infection, whereas crusted scabies is an infestation of the skin. Whereas scabies infestation is readily diagnosed, M. haemophilum infection poses a diagnostic challenge due to its rarity as well as varied clinical and histologic presentations. Although both scabies infestation and M. haemophilum have been reported in the literature separately, to our knowledge no previous reports have described these diseases occurring simultaneously in an iatrogenically immunosuppressed patient. We report herein a rare case of concomitant M. haemophilum and scabies infestation in a 38-year-old woman with dermatomyositis on multiple immunosuppressive agents.
2. Sampaio JL, Alves VA, Leão SC, et al. Mycobacterium haemophilum: emerging or underdiagnosed in Brazil?. Emerg Infect Dis. 2002;8(11):1359–60.
3. Walton SF, Beroukas D, Roberts-Thomson P, Currie BJ. New insights into disease pathogenesis in crusted (Norwegian) scabies: the skin immune response in crusted scabies. Br J Dermatol. 2008;158(6):1247–55.
4. Saubolle MA, Kiehn TE, White MH, Rudinsky MF, Armstrong D. Mycobacterium haemophilum: microbiology and expanding clinical and geographic spectra of disease in humans. Clin Microbiol Rev. 1996;9(4):435–47.
5. Lott JP, Werth VP, Kovarik CL. Cutaneous Mycobacterium haemophilum infection in iatrogenically immunocompromised patients without transplantation. J Am Acad Dermatol. 2008;59(1):139d–42.
6. Teh CL, Kong KO, Chong AP, Badsha H. Mycobacterium haemophilum infection in an SLE patient on mycophenolate mofetil. Lupus. 2002;11(4):249-52.
7. Seitz CS, Trautemann A, Bröcker EB, Abele-horn M, Goebeler M. Skin nodules in rheumatoid arthritis due to infection with Mycobacterium haemophilum. . 2008;88(4):428–9.
8. Lee WJ, Kang SM, Sung H, et al. Non-tuberculous mycobacterial infections of the skin: a retrospective study of 29 cases. J Dermatol. 2010;37(11):965–72.
9. Shah MK, Sebti A, Kiehn TE, Massarella SA, Sepkowitz KA. Mycobacterium haemophilum in immunocompromised patients. Clin Infect Dis. 2001;33(3):330–7.
10. Pedra e cal AP, Ferreira CP, Da Costa Nery JA. Crusted scabies in a patient with lepromatous leprosy. Braz J Infect Dis. 2016;20(4):399–400.
11. Barbosa júnior Ade A, Silva TM, Santos MI, et al. Coexistence of an unusual form of scabies and lepromatous leprosy. A case report. Pathol Res Pract. 1996;192(1):88–90.
12. Brondfield S, Reid M, Patel K, Ten R, Dhaliwal G. Disseminated mycobacterial infection and scabies infestation. Am J Med. 2015;128(10):e41–2.