Non-Invasive Genomic Profiling of Pigmented Lesions – an Interim Registry Analysis

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Greg Stevens
Burkhard Jansen
Terry Arnold
James Rock
Jennifer Wood
Mark Hyde
Loren Clarke

Keywords

pigmented lesion, noninvasive, genomic profiling

References

1. Gerami P, Yao Z, Polsky D, et al. Development and validation of a noninvasive 2-gene molecular assay for cutaneous melanoma. J Am Acad Dermatol. 2017;76(1):114-120.e2.

2. Jackson SR, Jansen B, Yao Z, Ferris LK. Risk Stratification of Severely Dysplastic Nevi by Non-Invasively Obtained Gene Expression and Mutation Analyses. SKIN The Journal of Cutaneous Medicine. 2020;4(2):105-110.

3. Brouha B, Ferris LK, Skelsey, MK, et al. Genomic Atypia to Enrich Melanoma Positivity in Biopsied Lesions: Gene Expression and Pathology Findings From a Large U.S. Registry Study. SKIN. 2021;5(1),13–18.

4. Brouha B, Ferris LK, Skelsey MK, et al. Real-World Utility of a Non-Invasive Gene Expression Test to Rule Out Primary Cutaneous Melanoma: A Large US Registry Study. J Drugs Dermatol. 2020;19(3):257-262.

5. Skelsey MK, Brouha B, Rock J, et al. Non-Invasive Detection of Genomic Atypia Increases Real-World NPV and PPV of the Melanoma Diagnostic Pathway and Reduces Biopsy Burden. SKIN. 2021;5(5), 512–523.

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