A Rare Presentation of Angiolymphoid Hyperplasia with Eosinophilia Involving the Scrotum

Main Article Content

Derrick Adams
Kevin Mai

Keywords

Angiolymphoid hyperplasia with eosinophilia, scrotum, vascular

Abstract

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare vascular proliferation that typically manifests as pink to reddish brown papules or nodules. These lesions classically affect the face or neck. Involvement of other structures including the tongue, colon, salivary glands, and muscle are rare. Male urogenital involvement for example, had less than 30 cases reported. Here we present the third reported case of ALHE involving the scrotum in a 17-year-old male.

References

1. Chun SI, Ji HG. Kimura's disease and angiolymphoid hyperplasia with eosinophilia: clinical and histopathologic differences. J Am Acad Dermatol. Dec 1992;27(6 Pt 1):954-8. doi:10.1016/0190-9622(92)70293-o

2. Azizzadeh M, Namazi MR, Dastghaib L, Sari-Aslani F. Angiolymphoid hyperplasia with eosinophilia and nephrotic syndrome. Int J Dermatol. Mar 2005;44(3):242-4. doi:10.1111/j.1365-4632.2004.02030.x

3. Adler BL, Krausz AE, Minuti A, Silverberg JI, Lev-Tov H. Epidemiology and treatment of angiolymphoid hyperplasia with eosinophilia (ALHE): A systematic review. J Am Acad Dermatol. Mar 2016;74(3):506-12.e11. doi:10.1016/j.jaad.2015.10.011

4. Ramchandani PL, Sabesan T, Hussein K. Angiolymphoid hyperplasia with eosinophilia masquerading as Kimura disease. Br J Oral Maxillofac Surg. Jun 2005;43(3):249-52. doi:10.1016/j.bjoms.2004.11.023

5. Tsuboi H, Masuzawa M, Katsuoka K. Angiolymphoid hyperplasia with eosinophilia affecting the nail bed and underlying bone. J Dermatol. Jun 2006;33(6):399-402. doi:10.1111/j.1346-8138.2006.00094.x

6. Chen JF, Gao HW, Wu BY, Tsai WC, Chiang CP. Angiolymphoid hyperplasia with eosinophilia affecting the scrotum: a rare case report with molecular evidence of T-cell clonality. J Dermatol. Apr 2010;37(4):355-9. doi:10.1111/j.1346-8138.2010.00818.x

7. Park J, Hwang SR, Song KH, Kim JI, Rhee CH, Yun SK. Angiolymphoid hyperplasia with eosinophilia affecting the scrotum of a child. Eur J Dermatol. 2013 May-Jun 2013;23(3):423-4. doi:10.1684/ejd.2013.2051

8. Wells GC, Whimster IW. Subcutaneous angiolymphoid hyperplasia with eosinophilia. Br J Dermatol. Jan 1969;81(1):1-14. doi:10.1111/j.1365-2133.1969.tb15914.x

9. Olsen TG, Helwig EB. Angiolymphoid hyperplasia with eosinophilia. A clinicopathologic study of 116 patients. J Am Acad Dermatol. May 1985;12(5 Pt 1):781-96. doi:10.1016/s0190-9622(85)70098-9

10. Dargent JL, Vannuffel P, Saint-Remy JM, Fisogni S, Facchetti F. Plasmacytoid dendritic cells in Kimura disease. Am J Dermatopathol. Dec 2009;31(8):854-6. doi:10.1097/DAD.0b013e3181a772c6

11. Chong WS, Thomas A, Goh CL. Kimura's disease and angiolymphoid hyperplasia with eosinophilia: two disease entities in the same patient: case report and review of the literature. Int J Dermatol. Feb 2006;45(2):139-45. doi:10.1111/j.1365-4632.2004.02361.x

12. Miller CJ, Ioffreda MD, Ammirati CT. Mohs micrographic surgery for angiolymphoid hyperplasia with eosinophilia. Dermatol Surg. Aug 2004;30(8):1169-73. doi:10.1111/j.1524-4725.2004.30349.x

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