Hydroxychloroquine and Acute Generalized Exanthematous Pustolosis

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Justine Galambus
Atefah Vafa


acute generalized exanthematous pustulosis, hydroxychloroquine, drug reactions


Acute generalized exanthematous pustulosis (AGEP) is a rare, potentially lethal, cutaneous reaction most commonly precipitated by drugs. Removal of the offending drug or treatment of the underlying infection usually results in recovery, though corticosteroids are often used to bolster treatment. We report a case of hydroxychloroquine-induced AGEP in an adult female. Though removal of hydroxychloroquine (HCQ) did largely resolve her rash, she continued to require corticosteroids over 200 days after she first began taking HCQ.


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