A Prospective, Multicenter, Randomized, Double-blind, Vehicle-controlled Phase 2 Study to Evaluate the Safety and Efficacy of a Combination Of 3% Minocycline and 0.3% Adapalene Topical Foam Formulation for the Treatment of Moderate-to-Severe Acne

Main Article Content

James Q Del Rosso
Linda Stein Gold
Zoe Draelos
Tooraj Joseph Raoof
Deidre Hooper
Iain Stuart

Keywords

Acne Vulgaris, Minocycline, Topical, Safety, Efficacy, Retinoid, Adapalene

Abstract

Abstract not available.

References

1. Thiboutot DM, Dréno B, Abanmi A, et al. Practical management of acne for clinicians: an international consensus from the Global Alliance to Improve Outcomes n Acne. J Am Acad Dermatol. 2018;78(2S1):S1-S23.e1.

2. Garner SE, Eady A, Bennett C, et al. Minocycline for acne vulgaris: efficacy and safety. Cochrane Database Syst Rev. 2012;CD002086.

3. Yentzer BA, Hick J, Reese EL, et al. Acne vulgaris in the United States: a descriptive epidemiology. Cutis. 2010;86:94-99.

4. Zaenglein AL, Pathy AL, Schlosser BJ, et al. Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol. 2016;74:945-973.

5. Garrido-Mesa N, Zarzuelo A, Gálvez J. Minocycline: far beyond an antibiotic. Br J Pharmacol. 2013;169:337-352.

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