APG777, a Humanized IgG1 Monoclonal Antibody, Binds to IL-13 with High Affinity and Potently Blocks IL-13 Signaling in Multiple in vitro Assays

Main Article Content

Eric Zhu
Paragon Therapeutics, Inc.

Hussam Shaheen
Paragon Therapeutics, Inc.

Carl Dambkowski
Apogee Therapeutics, Inc.

Jason Oh
Paragon Therapeutics, Inc.

Keywords

atopic dermatitis, IL-13, type 2 inflammation, eczema

References

1. Bieber T. Allergy 2020;75:54–62.

2. Hershey GK. J Allergy Clin Immunol 2003;111:677–90.

3. Gandhi NA, et al. Expert Rev Clin Immunol 2017;13:425–37.

4. Dall'Acqua, et al. J Biol Chem 2006;281:23514–24.

5. Zhu E, et al. EADV 2023 (poster #P0435).

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Published
Jan 16, 2024
DOI https://doi.org/10.25251/skin.8.supp.314

Article Details

How to Cite
Zhu, E., Shaheen, H., Dambkowski, C., & Oh, J. (2024). APG777, a Humanized IgG1 Monoclonal Antibody, Binds to IL-13 with High Affinity and Potently Blocks IL-13 Signaling in Multiple in vitro Assays. SKIN The Journal of Cutaneous Medicine, 8(1), s314. https://doi.org/10.25251/skin.8.supp.314
Issue
Vol. 8 No. 1 (2024): January 2024 Issue
Section
Atopic Dermatitis
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