Tapinarof Inhibits the Formation, Cytokine Production, and Persistence of Resident Memory T Cells In Vitro

Main Article Content

Nathan Mooney
Jessica E. Teague
Ahmed E. Gehad
Kimberly McHale
David S. Rubenstein
Rachael A. Clark

Keywords

Tapinarof, Aryl Hydrocarbon Receptor Agonist, Mechanism of Action, Resident Memory T Cell, Plaque Psoriasis, Remittive Effect, Topical

References

1. Dermavant Sciences. VTAMA (tapinarof) cream, 1%: US prescribing information. 2022. https://www.vtama.com/docs/DMVT_VTAMA_PI.pdf. Accessed December 2022.

2. Strober B, et al. J Am Acad Dermatol. 2022;87:800–806.

3. Matos TR, et al. J Clin Invest. 2017;127.11:4031–4041.

4. Lefevre MA, et al. Curr Opin Allergy Clin Immunol. 2021;21:355–360.

5. Zaid A, et al. Proc Natl Acad Sci U S A. 2014;111:5307–5312.

6. Larigot L, et al. Biochim Open. 2018;7:1–9.

7. Quintana FJ, et al. Nature. 2008;453:65–71.

8. Smith SH, et al. J Invest Dermatol. 2017;137:2110–2119.

Most read articles by the same author(s)