A Case of Systemic Anaplastic Large Cell Lymphoma with Secondary Cutaneous Involvement

Main Article Content

Andie Bulbin
NYITCOM

Sarah Stano
Kalliope Kyriakides
Paul Chu
Cindy Hoffman

Keywords

cutaneous lymphoma, ALCL, ALK-negative ALCL, sALCL

Abstract

Systemic anaplastic large cell lymphoma (sALCL) is a rare, malignant T-cell lymphoma characterized by CD30 expression. There are two subtypes: ALK-positive sALCL and ALK-negative sALCL. In either condition, extranodal involvement is uncommon. We report a unique case in a 75-year-old woman who presented with multiple crops of occasionally pruritic papules in different stages of healing along her back for 3-4 weeks. The patient also showed erythematous papules on her arms, as well as lymphadenopathy. After considering other cutaneous T-cell lymphomas, the ultimate diagnosis of ALK-negative sALCL was determined using the clinical data, results of punch biopsy, and immunohistochemical staining.  

References

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Published
Sep 15, 2023
DOI https://doi.org/10.25251/skin.7.5.21

Article Details

How to Cite
Bulbin, A., Stano, S., Kyriakides, K., Chu, P., & Hoffman, C. (2023). A Case of Systemic Anaplastic Large Cell Lymphoma with Secondary Cutaneous Involvement. SKIN The Journal of Cutaneous Medicine, 7(5), 1065–1066. https://doi.org/10.25251/skin.7.5.21
Issue
Vol. 7 No. 5 (2023): September 2023 Issue
Section
SKINmages: Clinical Images in Dermatology
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