A Review of Exogenous Factors Implicated in the Induction of Cutaneous Melanoma

Main Article Content

Jacob M Hands
Lawrence Moy


Cutaneous melanoma, Melanoma, Exogenous factors


Melanoma is an increasingly pervasive form of malignant skin cancer. Cases of cutaneous melanoma are on the rise across ages and global populations, with incidence increasing significantly for both men and women. Accordingly, the identification of modifiable behaviors is of paramount concern. Previous reviews have focused on specific risk factors (e.g. UVR, pollution, diet, hormonal supplementation) to the near exclusion of other contributory factors. This review strives to report an inclusive range of exogenous variables linked to cutaneous melanoma incidence. In this review, we examine the various contributions of exogenous factors linked to the induction of cutaneous melanoma. Factors for consideration include but are not limited to: long-wave Ultraviolet A (UVA), short-wave Ultraviolet B (UVB), hormonal supplementation, diet, smoking, alcohol, vitamin supplementation, ionizing radiation, pollution, and chemical exposure.


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