Merkel Cell Carcinoma Presenting as an Indurated Plaque

Main Article Content

Margaret Coleman Maxi
Joel Byrne
Ardenne Martin
Pamela Martin

Keywords

cellulitic presentation, cellulitis, Merkel cell carcinoma

Abstract

Merkel Cell Carcinoma (MCC) is a rare and aggressive neuroendocrine carcinoma that most commonly occurs in elderly Caucasian males who have a history of extensive sun exposure. Most cases of Merkel Cell Carcinoma (MCC) present in the outpatient setting and include a single, asymptomatic, red or pink lesion on sun exposed areas with a diameter less than 2 cm. There was a threefold increase in the incidence of MCC from 1986 to 2001, and the incidence of MCC is predicted to continue to increase secondary to the aging “baby boomer” population.To our knowledge, there are only two case reports that describe MCC resembling and receiving the diagnosis of cellulitis at initial presentation. We report an unusual case of MCC presenting as suspected cellulitis of the chest wall in an elderly Caucasian male.  

References

1. Paulson KG, Park SY, Vandeven NA, Lachance K, Thomas H, Chapuis AG, Harms KL, Thompson JA, Bhatia S, Stang A, Nghiem P. Merkel cell carcinoma: Current US incidence and projected increases based on changing demographics. Journal of the American Academy of Dermatology. 2018;78(3):457- 463.e2.

2. Hodgson NC. Merkel cell carcinoma: changing incidence trends. Journal of Surgical Oncology 2005;89:1-4.

3. Heath M, Jaimes N, Lemos B, Mostaghimi A, Wang LC, Peñas PF, Nghiem P. Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features. Journal of the American Academy of Dermatology. 2008 Mar;58(3):375-81.

4. Allen PJ, Bowne WB, Jaques DP, Brennan MF, Busam K, Coit DG. Merkel cell carcinoma: prognosis and treatment of patients from a single institution. Journal of Clinical Oncology. 2005 Apr 1;23(10):2300-9.

5. Acab JC, Kvatum W, Ebo C. A 76 year old male with an unusual presentation of merkel cell carcinoma. International Journal of Surgery Case Reports. 2016;23:177-81.

6. Safa F, Pant M, Weerasinghe C, Felix R, Terjanian T. Merkel cell carcinoma masquerading as cellulitis: a case report and review of the literature. Current Oncology. 2018 Feb;25(1):e106-e112.