Weight Gain Over Time in Hidradenitis Suppurativa Patients: Trends and Implications
Background: Hidradenitis suppurativa (HS) is often seen in overweight and obese patients. However, little is documented about weight gain over time in HS patients.
Methods: From August 2009 to March 2018, all patients in the UCLA HS clinic were asked at initial examination about their weight gain since high school.
Results: A cohort of 143 HS patients were found to have a significant mean BMI increase of 4.7 (25.5 to 30.2, p<0.0001) from high school until time of presentation (approximately a 15-year interval). Of the patients with ≥10 point BMI increase, 85.2% were women. 59.6% of women were normal weight in high school with an average BMI of 24.8 (SD 6.41, range 14-50) and 78.7% were overweight or obese at time of HS clinic intake. Hispanic HS patients were found to have more weight gain than other ethnic groups, (p=0.09) which may be clinically significant.
Conclusions: Although many HS patients were normal weight or mildly overweight in high school, most become obese in early adulthood. Since obesity is thought to increase HS severity, weight management should be stressed in HS patients early on before weight gain occurs.
Boer J, Nazary M, Riis PT. The Role of Mechanical Stress in Hidradenitis Suppurativa. Dermatol Clin. 2016;34(1):37-43. doi:10.1016/j.det.2015.08.011
Shlyankevich J, Chen AJ, Kim GE, Kimball AB. Hidradenitis suppurativa is a systemic disease with substantial comorbidity burden: A chart-verified case-control analysis. J Am Acad Dermatol. 2014;71(6):1144-1150. doi:10.1016/j.jaad.2014.09.012
Tzellos T, Zouboulis CC, Gulliver W, Cohen AD, Wolkenstein P, Jemec GBE. Cardiovascular disease risk factors in patients with hidradenitis suppurativa: A systematic review and meta-analysis of observational studies. Br J Dermatol. 2015;173(5):1142-1155. doi:10.1111/bjd.14024
Egeberg A, Gislason GH, Hansen PR. Risk of Major Adverse Cardiovascular Events and All-Cause Mortality in Patients With Hidradenitis SuppurativaCardiovascular Events and All-Cause Mortality in Hidradenitis SuppurativaCardiovascular Events and All-Cause Mortality in Hidradenitis Suppurativa. JAMA Dermatology. 2016;152(4):429-434. doi:10.1001/jamadermatol.2015.6264
Nazary M, Van Der Zee HH, Prens EP, Folkerts G, Boer J. Pathogenesis and pharmacotherapy of Hidradenitis suppurativa. Eur J Pharmacol. 2011;672(1-3):1-8. doi:10.1016/j.ejphar.2011.08.047
Schrader AMR, Deckers IE, Van Der Zee HH, Boer J, Prens EP. Hidradenitis suppurativa: A retrospective study of 846 Dutch patients to identify factors associated with disease severity. J Am Acad Dermatol. 2014;71(3):460-467. doi:10.1016/j.jaad.2014.04.001
Riis PT, Saunte DM, Benhadou F, Marmol V, Guillem P, Beksac B. Low and high body mass index in hidradenitis suppurativa patients — different subtypes ? J Eur Acad Dermatology Venereol. 2018;32(2):307-312. doi:10.1111/jdv.14599
Thomas CL, Gordon KD, Mortimer PS. Rapid resolution of hidradenitis suppurativa after bariatric surgical intervention. Clin Exp Dermatol. 2014;39(3):315-318. doi:10.1111/ced.12269
Gallagher C, Kirthi S, Burke T, O’Shea D, Tobin AM. Remission of hidradenitis suppurativa after bariatric surgery. JAAD Case Reports. 2017;3(5):436-437. doi:10.1016/j.jdcr.2017.06.008
Gierach M, Gierach J, Ewertowska M, Arndt A, Junik R. Correlation between Body Mass Index and Waist Circumference in Patients with Metabolic Syndrome. ISRN Endocrinol. 2014;2014(514589).
Shalom G, Freud T, Harman-Boehm I, Polishchuk I, Cohen AD. Hidradenitis suppurativa and metabolic syndrome: A comparative cross-sectional study of 3207 patients. Br J Dermatol. 2015;173(2):464-470. doi:10.1111/bjd.13777
Fryar CD, Gu Q, Ogden CL, Flegal KM. Anthropometric Reference Data for Children and Adults: United States, 2011-2014. Vital Health Stat 3. 2016;(39):1-46.
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