Clinically Important Considerations with the Use of Oral Doxycycline

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James Del Rosso


doxycycline, tetracyclines, therapy, therapeutic tips, drug reactions


Tetracyclines are the most commonly prescribed oral antibiotics in dermatology. They are used to treat both cutaneous infections and non-infectious inflammatory disorders, the latter often with chronic therapy. Doxycycline may be favored by some dermatologists over minocycline due to a lower risk of certain adverse reactions, especially some with systemic manifestations. The major adverse events that are more common with doxycycline are gastrointestinal side effects, including pill esophagitis, and phototoxicity. This article reviews practical tips when prescribing oral doxycycline, emphasizing suggestions to optimize therapeutic success and reduce untoward reactions.      


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