Rapid Reduction and Free or Almost Free of Itch Response With Oral Difelikefalin in Subjects With Notalgia Paresthetica and Moderate-to-Severe Pruritus

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Mark Lebwohl
Brian S. Kim
Javier Alonso-Llamazares
Zoe Diana Draelos
Kristine Nograles
Joana Goncalves
Joshua Cirulli
Jennifer A. Mohawk
Catherine Munera
Tom Xue
Robert Bissonnette




1. Mülkoğlu C, Nacır B. BMC Neurol. 2020;20:191.

2. Kim BS, et al. A phase 2 study of oral difelikefalin for moderate-to-severe pruritus in subjects with notalgia paresthetica (KOMFORT). Presented at: the 31st European Academy of Dermatology and Venereology (EADV) Congress; September 7–10, 2022.

3. Kim BS, et al. N Engl J Med. 2023;388:511-517. 4. Bacci ED, et al. JAAD Int. 2022;8:94-101. 5. Naegeli AN, et al. Int J Dermatol. 2015;54:715-722.

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