Syringofibroadenomas of the Bilateral Lower Extremities

Main Article Content

Jordan Bury
Sean Igelman
H Nicholas Shamma
Julian Trevino


eccrine gland, skin neoplasms, syringofibroadenoma, adnexal tumor


Syringofibroadenoma is a rare adnexal tumor which is derived from the acrosyringial cells of the eccrine ducts. The presentation of this lesion is variable and nonspecific, making the diagnosis, based off presentation alone, difficult. With a wide differential, more information is necessary in order to properly diagnose. Histopathological findings for syringofibroademona have distinct pathological features. Histological features are reviewed and options for treatment are discussed.


1. Tey, H. L., et al. “Leprosy-Associated Eccrine Syringofibroadenoma of Mascaro.” Clinical and Experimental Dermatology, vol. 32, no. 5, 2007, pp. 533–535.,

2. Bottino, Caroline Bertolini, et al. “Solitary Eccrine Syringofibroadenoma - Case Report.” Anais Brasileiros De Dermatologia, vol. 90, no. 3 suppl 1, 2015, pp. 235–238.,

3. Andrade, Ana Carolina, et al. “Clouston Syndrome Associated with Eccrine Syringofibroadenoma.” Anais Brasileiros De Dermatologia, vol. 89, no. 3, 2014, pp. 504–506.,

4. Riera‐Monroig, Josep, et al. “Eccrine Syringofibroadenoma as a Clue for the Diagnosis of Schöpf‐Schulz‐Passarge Syndrome in Acquired Palmoplantar Keratoderma.” Journal of Cutaneous Pathology, vol. 47, no. 10, 2020, pp. 987–989.,

5. Bjarke, Torsten, et al. “Carcinoma and Eccrine Syringofibroadenoma: A Report of Five Cases.” Journal of Cutaneous Pathology, vol. 30, no. 6, 2003, pp. 382–392.,