Cutaneous Implications of Whole Body Cryotherapy

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Aaron S. Farberg
Stephen Donohue
Alexander Farberg
Rebeca W. Teplitz
Darrell S. Rigel


cryotherapy, sub-freezing, temperature, recovery, exercise, rehabilitation, skin, rejuvenation


Whole body cryotherapy (WBC) is a medical treatment utilizing sub-freezing temperatures to enhance recovery after exercise and facilitate injury rehabilitation. Recently the therapy has been advocated to help skin appear and feel healthier, fight age-related deficiencies, and increase antioxidant production. The currently available evidence appears to be insufficient to support the use of WBC for improving skin and there is some small potential for risk. There are no well-controlled studies evaluating the clinical effects of WBC on the skin. Although there is selected data to support possible theories for WBC’s purported skin rejuvenation effects, the evidence at this time remains limited. Further investigation may be warranted to determine if WBC can actually have a proven beneficial effect on skin.


Costello JT, Baker PRA, Minett GM, Bieuzen F, Steward IB, Bleakley C. Whole-body cryotherapy (extreme cold air exposure) for preventing and treating muscle soreness after exercise in adults. Cochrane Database Syst Rev. 2015;9:CD010789.

Banfi G, Lombardi G, Colombini A, Melegati G. Whole-body cryotherapy in athletes. Sports Med. 2010;40;509-517.

Hirvonen HE, Mikkelsson MK, Kautiainen H, Pohjolainen TH, Leirisalo-Repo M. Effectiveness of different cryotherapies on pain and disease activity in active rheumatoid arthritis. A randomized single blinded controlled trial. Clin Exp Rheumatol. 2006;24;295-301.

Mickle K. Cryotherapy promises to burn 800 calories in 3 minutes. Shape Magazine. Feb 17, 2015.

Deonizio J, Werner B, Mulinari-Brenner FA. Histological comparison of two cryopeeling methods for Photodamaged skin. ISRN Dermatol. 2014:950754.

Chiarello SE. Cryopeeling (extensive cryosurgery) for treatment of actinic keratoses: an update and comparison. Dermatolog Surg. 2000;26:728–732.

Roy D. Ablative facial resurfacing. Dermatol Clin. 2005;23(3):549-59.

Bleakley CM, Bieuzen F, Davison GW, Costello JT. Whole-body cryotherapy: empirical evidence and theoretical perspectives. Sports Med. 2014;5:25-36

Costello JT, Culligan K, Selfe J, Donnelly AE. Muscle, Skin and Core Temperature after -110°C Cold Air and 8°C Water Treatment. PLoS ONE. 2012;7(11):e48190.

Costello J, McInerney CD, Bleakley CM, Selfe J, Donnelly A. The use of thermal imaging in assessing skin temperature following cryotherapy: a review. J Therm Biol. 2012;37:103–110.

Carruthers J, Stevens WG, Carruthers A, Humphrey
S. Cryolipolysis and skin tightening. Dermatol Surg. 2014;40Suppl12:S184-9.

Cryo: Beauty & Anti-Aging. Available: URL: Accessed: 5/31/2016

Texas Cryotherapy: Cryotherapy Benefits. Available: URL: Accessed: 5/31/2016

Albert-Beitch C. You’ve heard of brain freeze--How about a whole body freeze? Inc Magazine. Dec 4, 2014.

Pump B, Shiraishi M, Gabrielsen A, Bie P, Christensen NJ, Norsk P. Cardiovascular effects of static carotid baroreceptor stimulation during water immersion in humans. Am J Physiol Heart Circul Physiol. 2001;280:H2607–H2615.

Szygula R, Dybek T, Klimek A, Tubek S. Impact of 10 sessions of whole body cryostimulation on cutaneous microcirculation measured by laser Doppler flowmetry. J Human Kinetics. 2011;30:75-83.

Miller E, Markiewicz L, Saluk J, Majsterek I. Effect of short-term cryostimulation on antioxidative status and its clinical applications in humans. Eur J Appl Physiol. 2012;112:1645–1652.

Bleakley CM, Davison GW. What is the biochemical and physiological rationale for using cold-water immersion in sports recovery? A systematic review. Br J Sports Med. 2010;44:179–187.

Mila-Kierzenkowska C, Woz´niak A, Woz´niak B, et al. Whole body cryostimulation in kayaker women: a study of the effect of cryogenic temperatures on oxidative stress after the exercise. J Sports Med Phys Fitness. 2009;49:201–207.