Bazex Syndrome Associated with Angioimmunoblastic T-cell Lymphoma

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Gregory Ugoh Ugoh
The University of Texas Medical Branch at Galveston (John Sealy School of Medicine)

Anthony Linfante
Allison Good
Janice Wilson
Kathleen Kroger

Keywords

acrokeratosis, angioimmunoblastic, bazex, erythematous, lymphoma, paraneoplastica, psoriasiform

Abstract

Bazex syndrome, also known as Acrokeratosis paraneoplastica, is a paraneoplastic disorder characterized by erythematous psoriasiform plaques involving the nose, ears, and acral sites. Although classically associated with squamous cell carcinomas of the upper aerodigestive tract, it has also been reported in association with adenocarcinoma, genitourinary tumors, multiple myeloma, and rarely, peripheral T-cell lymphoma and follicular lymphoma in-situ. Herein, we present a patient with Bazex syndrome associated with angioimmunoblastic T-cell lymphoma (AITL), a rare association not previously reported in the literature.  

References

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2. Bazex A, Salvador R, Dupré A, et al. Syndrome paranéoplasique à type d'hyperkératose des extrémités: guérison après le traitement de l'épithélioma laryngé. Bull Soc Fr Dermatol Syphiligr. 1965;72:182.

3. Santos-Silva AR, Correa MB, Vargas PA, Almeida OP, Lopes MA. Bazex syndrome (acrokeratosis paraneoplastica) diagnosed in a patient with oral persistent ulcerations. Head Neck Pathol. 2010;4(4):312-317. doi:10.1007/s12105-010-0203-5

4. Eckstein J et al. A series of typical and atypical cases of Bazex syndrome: Identifying the red herring to avoid delaying cancer treatment. Clin Case Rep. 2020;8(11):2259-2264.

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Published
May 20, 2023
DOI https://doi.org/10.25251/skin.7.3.14

Article Details

How to Cite
Ugoh, G. U., Linfante, A., Good, A., Wilson, J., & Kroger, K. (2023). Bazex Syndrome Associated with Angioimmunoblastic T-cell Lymphoma. SKIN The Journal of Cutaneous Medicine, 7(3), 834–836. https://doi.org/10.25251/skin.7.3.14
Issue
Vol. 7 No. 3 (2023): May Issue and Posters from WCH23 & WCM23
Section
Brief Articles
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