Clinical Management of Actinic Keratosis: Review and Update

Main Article Content

Haowei Han
Brian Berman


Nonmelanoma skin cancer, actinic keratosis, squamous cell carcinoma, clinical management


Actinic keratosis is commonly seen in dermatology clinics. Age and chronic sun exposure are the essential risk factors for its pathogenesis. It is regarded as a premalignant lesion; hence, aggressive treatment is warranted. Abundant research has been published about overall management, however, extensive knowledge about actinic keratosis prevention, the cost, safety profile, and mechanism of the existing therapeutics are pivotal in optimal clinical care. In this review article, we hereby present several commonly used approaches in office settings and the current guidelines. Finally, we will discuss the limitations of the available clinical evidence.


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