Bilateral Nodules on the Thighs: A Case Report on Insulin Therapy-Induced Palisaded Granulomas

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Tara Snow
Chelsea D. Harper
Jonathan Crane
Muammar Arida


nodules, Palisaded, Granulomas, thighs


As the incidence and prevalence of Diabetes Mellitus is increasing, more cases of dermatologic complications attributed to therapy are being reported. Injection site reactions, most commonly erythema, edema and induration, lipohypertrophy, and lipoatrophy have been associated with subcutaneous insulin therapy. Accurate diagnosis is important to guide clinical management and to ensure appropriate blood glucose control. Herein, we present an unusual case of bilateral nodules on the thighs secondary to insulin injections.


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