Coexisting Pediatric Acute Generalized Exanthematous Pustulosis and Staphylococcal Scalded Skin Syndrome

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Cassandra Beard
Rafael Mojica
Sarah Ferrer-Bruker
Karthik Krishnamurthy


Drug reaction, Pediatric, acute generalized exanthematous pustulosis, AGEP, Staphylococcal scalded skin syndrome, SSSS


Acute Generalized Exanthematous Pustulosis is a rare drug-induced skin disorder that can present at any age. It is typically noted by swelling and erythema, with numerous facial and/or anogenital nonfollicular pustules that quickly disseminate. Staphylococcal scalded skin syndrome presents with erythema and swelling that similarly favor the head and intertriginous sites with subsequent bullae formation. We present a case of a four-year-old female who presented with SSSS complicated by the development of AGEP and discuss the course of her condition and treatment.


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